AddThis Sharing ButtonsShare to FacebookFacebookFacebookShare to TwitterTwitterTwitterShare to EmailEmailEmailShare to RedditRedditRedditShare to MoreAddThisMoreA Rottweiler named Molly is “showing her softer side, using her maternal instincts to help rear two lambs” that had been born with complications on an English farm — and she is fiercely protective… (photos and story by BBC) Thanks to member MJ Allen for the link!AddThis Sharing ButtonsShare to FacebookFacebookFacebookShare to TwitterTwitterTwitterShare to EmailEmailEmailShare to RedditRedditRedditShare to MoreAddThisMore
Email Share Share on Facebook LinkedIn Share on Twitter New research suggests that a subgroup of people may respond differently to the drug ecstasy thanks to reductions in a molecule that regulates serotonin signaling between brain cells. The study has been published in the Journal of Psychopharmacology.“My research group is interested in how genetic and/or early environmental factors shape our brain and behaviour. Particularly as we know that these factors play a crucial role in our susceptibility to psychiatric disorders,” said study author Bart A. Ellenbroek of Victoria University of Wellington and the Behavioural Neurogenetics Group.“In this study, we investigated to what extent a genetic disruption of the serotonin transporter (a key protein involved in the regulation of the neurotransmitter serotonin) in rats affects the response to MDMA (the active ingredient of ecstasy).” Pinterest The serotonin transporter is a protein acts like a vacuum for serotonin, sucking up the neurotransmitter after it has been used for neuronal signaling. Rats that lacked this protein had trouble discriminating between the effects of MDMA and the stimulate amphetamine.Both MDMA and amphetamine increase levels of dopamine, noradrenaline, and serotonin in the brain. But the findings suggest that MDMA’s effects are much more strongly impacted by serotonin.The findings also have some implications for humans.“Genetic reductions in the serotonin transporter are very common in humans (in the Western world about 30% of people have a reduction). Thus our study suggests that humans are likely to respond very differently as well,” Ellenbroek told PsyPost.“While ecstasy has a relatively low risk of leading to addiction, our study (as well as previous papers from our group) suggest that in these genetically vulnerable rats, ecstasy is much more addictive.”But the research — like all studies — includes some limitations.“There are two major caveats. First, the rats have a stronger genetic reduction in the serotonin transporter than humans typically have, and thus we would need to repeat this study with rats with a reduction similar to humans,” Ellenbroek explained.“Secondly, and most importantly, rats are not small humans, and while the basic pharmacology between rats and humans is quite similar, the translation from animal to human research is notoriously difficult. Thus studies in humans are essential to confirm (or disprove) our claims.”The study, “A genetic deletion of the serotonin transporter differentially influences the behavioural effects of MDMA”, was authored by Michaela Pettie, Alana Oakly, David N. Harper and Bart A. Ellenbroek.
Over the weekend and through today the Democratic Republic of the Congo (DCR) reported 13 new Ebola cases in several outbreak areas, as neighboring South Sudan prepared to vaccinate healthcare and frontline workers in bordering regions.New cases in multiple locationsOf the 13 new cases, 3 are in Mabalako, one of the initial hot spots that has seen a recent resurgence of Ebola activity. Four patients are from Katwa, an area just east of Butembo, and 2 are in Beni, the outbreak’s main epicenter. Four more locations each reported 1 case: Mambasa, Kyondo, Butembo, and Vuhovi.In its Dec 8 update, the DRC health ministry added 8 older cases to the total, part of ongoing efforts to clean up the database. That and the new cases lifts the overall outbreak total to 498 cases, 450 of them confirmed and 48 listed as probable.Also over the past 3 days, the health ministry reported 9 more deaths, including 2 in Beni, 2 in Mabalako, 2 in Butembo, and 1 each in Mambasa, Katwa, and Vuhovi. The death toll as of today stands at 285.The two patients from Mabalako and the ones from Katwa and Vuhovi are all listed as community deaths, occurrences that pose a high risk of spread, given that Ebola virus levels are highest during severe illness and at the time of death. Also, those caring for sick people at home don’t have the personal protective equipment found in Ebola treatment units.In its update today, the health ministry said that, over the past 6 weeks, Ebola cases and deaths have been increasing in Butembo and Katwa because of community resistance, health infrastructure destructions, and physical aggression faced by response teams. At a media briefing in Kinshasa on Dec 6, Heath Minister Oly Ilunga Ilunga, MD, called the increase disturbing and said more teams are being sent to Butembo, a major urban area, and surrounding health zones to strengthen response operations.Health officials are still investigating 73 suspected Ebola cases. In its Dec 8 report, the health ministry said a patient who died from a suspected Ebola infection at a hospital about 62 miles northwest of Goma, the provincial capital, tested negative for the disease. It commended the hospital’s medical team for calling the toll-free emergency number, isolating the patient’s body, and identifying contacts while lab testing was under way.Meanwhile, the number of people vaccinated continues to rise, and the VSV-EBOV campaign has immunized 43,944 people.South Sudan to immunize at-risk peopleIn other outbreak developments, South Sudan’s health ministry, with support from several health partners, including the World Health Organization (WHO) and Gavi, the Vaccine Alliance, announced plans to vaccine healthcare and frontline workers in high-risk states that border the DRC.South Sudan is one of three DRC neighbors deemed to be at very high risk of Ebola importation. The country is on high alert, but no confirmed cases have been detected. The step is part of South Sudan’s national preparedness efforts and follows a similar campaign announced last month to vaccinate the same groups against Ebola in Uganda.In a Dec 8 statement, the WHO’s South Sudan office said a 60-person vaccination team underwent 4 days of training in the country’s capital city of Juba last week. Members are from four states: Juba, Yei, Yambio, and Nimule.According to the WHO, 2,160 doses of VSV-EBOV, Merck’s experimental Ebola vaccine, have been allocated for the South Sudan campaign, and vaccination is slated to begin on Dec 19 in Juba. Those who are vaccinated will be followed up for 21 days.See also:Dec 8 DRC updateDec 9 DRC updateDec 10 DRC updateDec 8 WHO South Sudan office statement
Author: AP Do you see a typo or an error? Let us know. Published: September 30, 2016 1:24 PM EDT CHICAGO (AP) – The man who got generations of hot dog lovers humming along to the Oscar Mayer Weiner song has died.An obituary posted online by a northern Illinois funeral home says Richard Trentlage died on Sept. 21 at age 87.With the words, “Oh, I wish I were an Oscar Mayer wiener,” Trentlage helped solidify the company’s hot dogs as a piece of Americana.The jingle he wrote appeared in a 1960s television commercial featuring cartoon children marching along and singing. The tune remained a fixture for the next half a century.Trentlage was born in Chicago and began penning jingles as a high school student. Later, he transformed his living room into a recording studio, inviting his own children to sing on audition tapes. Man got generations humming Oscar Mayer wiener song dies SHARE
Allen & Overy has hiked pay for its newly qualified solicitors, becoming the third magic circle firm to offer more than £80,000 for fresh-faced solicitors.The firm confirmed a 3% rise in NQ pay this morning, meaning that its September cohort will now gross £81,000, up from £78,500.This puts it ahead of Linklaters (£78,500) and Slaughter and May (£78,000) but slightly behind Freshfields Bruckhaus Deringer, which pays its NQs £85,000, and Clifford Chance (£87,300).The traditional elite firms in the UK have been hit by competition in recent years by US firms offering NQ salaries in excess of £100,000.Under A&O’s new pay scheme, first year trainees will earn £44,000, up from from £42,000 (4.7%) while second year trainees will see pay increased from £47,000 to £49,000.Trainee salaries at A&O now higher than at counterparts Freshfields, Slaughter and May and Linklaters. Those firms pay £43,000 in the first year. In the second year Fresfields and Slaughter and May pay £48,000 while Linklaters pays £49,000.Clifford Chance leads the way, with first-year trainees on £44,000, rising to £50,500 in the second year.
[av_one_full first min_height=” vertical_alignment=” space=” custom_margin=” margin=’0px’ padding=’0px’ border=” border_color=” radius=’0px’ background_color=” src=” background_position=’top left’ background_repeat=’no-repeat’ animation=”][av_heading tag=’h3′ padding=’10’ heading=’Ceres stuns S’pore Tampines at Panaad Stadium to surge in AFC’ color=” style=’blockquote modern-quote’ custom_font=” size=” subheading_active=’subheading_below’ subheading_size=’15’ custom_class=”]By ADRIAN STEWART CO[/av_heading][av_textblock size=” font_color=’custom’ color=”]Thursday, March 9, 2017[/av_textblock][av_image src=’http://www.panaynews.net/wp-content/uploads/2017/03/sports-Ceres.jpg’ attachment=’99096′ attachment_size=’full’ align=’center’ styling=” hover=” link=” target=” caption=’yes’ font_size=’14’ appearance=’on-hover’ overlay_opacity=’0.4′ overlay_color=’#000000′ overlay_text_color=’#ffffff’ animation=’no-animation’]Ceres-Negros Football Club stars Kevin Ingreso (6) and Roland Müller (2nd from right) and the rest of the team wave to their Negrense fans after a rousing victory over the Tampines Rovers in the 2017 AFC Cup group stage on Tuesday night at the Panaad Park and Stadium in Bacolod City. ARCHIE ALIPALO/PN[/av_image] [av_textblock size=” font_color=” color=”]MANILA – The Ceres-Negros Football Club did not disappoint its hometown fans as it scored a 5-0 win over Singapore’s Tampines Rovers in the 2017 AFC Cup group stage on Tuesday night at the Panaad Park and Stadium in Bacolod City.Bienvenido Marañon fired two goals, while Iain Ramsay, Manuel Ott and Fernando Rodriguez added a conversion each for Ceres-Negros which bounced back from a 1-1 draw with Vietnam.With the victory, the Bacolod City-based squad is currently at solo first place in Group G with four points, followed by the Tampines Rovers with three, Hanoi with two and Felda United with one point.Ramsay opened the scoring for the Ceres Negros with his left foot hit from outside the box. The lead was quickly doubled as Marañon was left wide open after Tampines Rovers came out of the goal area.The Tampines Rovers also had opportunities of their own late in the first half but failed to come up with a decent shot. Ceres-Negros closed out the first half with another hit by Ott from outside the box.Ceres-Negros continued its rampage in the second half as Ramsay passed the ball to Marañon for a beautiful finish. The Negrenses ended the dominant win with a goal from newcomer Rodriguez from a pass by Jeffrey Christiaens.“I think the crowd provided the special motivation for the players,” said Ceres Negros head coach Risto Vidakovic. “But like what I said if we play together we can get the result that we wanted.”Ceres-Negros will hope for its second straight victory in the group stage when it faces the lowly Felda United of Malaysia at 7:30 p.m. on March 15 still at the Bacolod City venue. Ceres-Negros needs to top their group for them to advance in the zonal semifinals and play against the Asia zone winner, with the winner moving up to the zonal finals./PN[/av_textblock][/av_one_full]
Soccer Romellu Lukaku is reportedly in contention to start against Chelsea after shaking off an ankle injury. The Belgian striker has been sidelined for the past two weeks after hobbling off against Arsenal last month. Lukaku missed Manchester United’s final three Premier League games of the season, as he returned to Belgium to receive treatment. United were tempted to recall Lukaku for the final league encounter of the season, but decided it was best to save the 25-year-old for the FA Cup final. Lukaku returned to training on Tuesday and is now in line to start against his former side, the Sun claim. Chelsea and United go toe-to-toe in the final, with both sides desperate to add some silverware to a disappointing season. United were convincingly beaten by Manchester City to the league title, while Chelsea missed out on Champions League football by finishing fifth in the table. The return of Lukaku will be a major boost to United who rely on the goals from their No.1 striker. Lukaku has bagged 27 goals in his first season at United and will be hoping to end his debut campaign with a trophy.
Sverev, Busta and Brady also made it to the semifinalsNew York: Former champion Naomi Ozaka US Open Reached the semi-finals of the Grand Slam Tennis Tournament 6-3, 6 – in straight sets against Real Madrid. The Osaka semi-final was held at 4 p.m. The match ended in 20 minutes.Jenny is an American actress who is amazing this time around Forbody is Osaka’s opponent in the semi – finals Lukashenko’s Yulia Putin defeated Seva 6-3, 6-2 Tucky reaches Brady’s first Grand Slam semifinal German star Alexander Schweizerwei in the Shaw Singles Shiite star Borna Corichie 1-6, 7-6, 7-6, 6-6 The fall reached the last channel and lasted for 3 hours and 25 minutes Sverev Korichi’s challenge in the middle of the night Second Grand Slam semi-final appearance in a row He is also in the Australian Open this year It was in Mi.Quarterback on the controversial match that disqualified Djokovic The Spanish Spaniard Pablo Carr Nobusta is five sets long 3-6, 7- 6,7 -6,0 – 6, 6 -3 Danny crossed the shop and reached the semifinals at 4 p.m. The battle lasted for about 8 minutes Eligibility for the second U.S. Open Semi in Staten’s career Won.
By Bruce FuhrThe Nelson Daily SportsIt’s going to be a survival of the fittest for the L.V. Rogers Junior Bombers.Playing with six players after starter Adam Berg went down with a broken arm last week during training and losing another in the tournament, the Junior Bombers ran out of gas in a 47-45 loss to Mount Boucherie Bears in action Saturday at the Kelowna Secondary School Junior Boy’s Basketball Tournament in the Central Okanagan.“The team has experienced some harsh injuries this year,” said Junior Bombers Vivian Kingdon. “Isaiah Kingdon has recently returned for his first set of games this past weekend after breaking his ring finger on his left hand. “Last week at practice our 6’4″ post Adam Berg broke his arm and will not be returning to the hardwood this season.”Still LVR played the Bears tough, led by Matt Zukowski with 23 points and Isaiah Kingdon with 12.LVR opened the tournament with a sluggish performance, losing to Abbotsford 70-48. Foul trouble combined with a slow start did the Bombers in against the Fraser Valley squad.Zukowski led the Bomber attack once again with 13 points while center McLain Sandeveland and Jack Sturrup scored 12 and 11 points, respectively.LVR rebounded Saturday to knock off the Fulton Maroons 53-40. Sandeveland scored a game-high 19 points to lead the Bombers. Kingdon and Zukowski each had 10.During the contest the Bombers lost Sturrup to an ankle injury to reduce the roster to six players.The Bombers return to action January 28-29 with a mini tournament at the Hangar.The event is a preview to a huge test for LVR as the Bombers travel to Edmonton February 17-19 to compete in the Tri-Provincial Tournament host by Harry Ainley Secondary [email protected]
Rd. This year marks the 12th consecutive that the Southland has produced at least 10 selections. The three-time regular season champion Sam Houston State had five players selected with right-hander pitcher Tyler Eppler being the first Bearkat drafted in the sixth round by the Pittsburgh Pirates. Nine Southland schools were represented with Sam Houston, Lamar (three), Oral Roberts (three), Southeastern Louisiana (two), Abilene Christian (one), Central Arkansas (one) McNeese State (one), Nicholls (one) and Northwestern State. Oakland L.A. Dodgers 17 Tyler Eppler, RHP Taylor Byrd, LHP 7 The five players selected from Sam Houston is a school record for the Bearkats. Joining Eppler was first baseman Ryan O’Hearn (Kansas City Royals; eighth round), shortstop Corey Toups (Kansas City; 15th round), third baseman Carter Burgess (Tampa Bay Rays; 28th round) and center fielder Colt Atwood (Oakland Athletics; 38th round). Seth Spivey, C Carter Burgess, 3B 2014 Southland Conference Draft Picks 453 22 Kansas City Sam Bumpers, SS Colorado Lamar 35 521 Oral Roberts The Rangers had the most Southland selections with three followed by the Pirates, Royals, Rockies and Blue Jays with two apiece. The Twins, Mariners, Giants, Astros, Dodgers, Rays, Brewers and Athletics each selected one. Lamar was another conference team with multiple draftees. The 2014 Southland Hitter of the Year Sam Bumpers was the first Cardinal called in the draft. The senior shortstop was picked by Colorado in the 22nd round. Two Cardinal pitchers were also picked with right-hander J.T. Autrey in the 32nd by Toronto and left-hander David Carver in the 35th round to the Milwaukee Brewers. Oral Roberts 276 Jordan Romano, RHP 9 23 Milwaukee Jose Trevino, 3B 653 191 186 Nicholls 8 Player, Pos. Texas Kansas City Sam Houston State Gavin Glanz, RHP 38 Texas Doug Votoloto, CF 6 Colorado 294 MLB Team College Lamar 10 306 McNeese State 243 Abilene Christian 15 David Carver, LHP 32 Pittsburgh Colt Atwood, CF 847 Sam Houston State Pittsburgh 7 Lamar 20 598 23 Conference tournament champion Southeastern Louisiana saw twoplayers drafted, including the league’s newcomer of the year Andrew Godbold. The Lion right fielder was picked by the Los Angeles Dodgers in the 23rd round. Right-hander Andro Cutura was the first Lions player selected, going in the seventh round to the Minnesota Twins. Southeastern Louisiana 699 Bret Underwod, CF 201 Central Arkansas Oral Roberts Ryan O’Hearn, 1B 683 Oral Roberts third baseman Jose Trevino was the first league player drafted, going five spots ahead of Eppler in the sixth round to the Texas Rangers. Two other Golden Eagles were drafted with Trevino, including right-handed pitcher Jordan Romano in the 10th round by the Toronto Blue Jays and right-handed pitcher Gavin Glanz in the 23rd round by the Colorado Rockies. The signing deadline is July 18. 28 FRISCO, Texas – The Southland Conference had 18 selections in the 2014 Major League Baseball First-Year Player Draft, including four league teams with multiple draftees. Seattle Toronto Southeastern Louisiana 6 Andrew Godbold, LF Minnesota 954 1046 San Francisco Toronto Tampa Bay Corey Toups, SS Michael Clemens, RHP Northwestern State 200 Andro Cutura, RHP Sam Houston State 10 Texas J.T. Autrey, RHP 1152 Pick Sam Houston State Sam Houston State